5-Amino-1MQ
Also known as 5-amino-1-methylquinolinium, NNMT inhibitor
5-Amino-1MQ is a small-molecule NNMT inhibitor — not a peptide — studied as a research compound in metabolic-enzyme science. Its research-use profile: chemistry, the NNMT target, and handling.
The first thing to correct about 5-Amino-1MQ is a common misfiling: it is not a peptide. It is a small-molecule compound — a substituted quinolinium — and it has no amino-acid sequence to report. It shares this store's Metabolic category with a set of peptides, but chemically it is a different kind of thing entirely.
What it is studied as, in the research literature, is an inhibitor of a specific enzyme: nicotinamide N-methyltransferase, usually abbreviated NNMT. This page describes that enzyme target and the compound's chemistry, and — consistent with the rest of the store — makes no therapeutic, metabolic-outcome, or efficacy claims. It is presented as a research compound only.
A small-molecule quinolinium compound (5-amino-1-methylquinolinium), studied as an inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Unlike the other compounds in this category, it is not a peptide at all — it has no amino-acid sequence and is a synthetic small molecule. Described strictly as a research compound.
A small molecule, not a peptide
5-Amino-1MQ (5-amino-1-methylquinolinium) is built on a quinolinium ring system, not on a chain of amino acids. That means the usual peptide descriptors — sequence, residue count, disulfide bonds — simply do not apply. When a certificate of analysis for this compound looks different from a peptide's, that is expected: it is characterized as a small molecule.
This distinction matters for anyone organizing a metabolic-research bench, because 5-Amino-1MQ is handled, stored, and analyzed like a small-molecule reagent rather than like a lyophilized peptide.
The NNMT enzyme it targets
Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that transfers a methyl group to nicotinamide. It sits at a junction of methylation and NAD-related metabolism, which is why enzyme researchers pay attention to molecules that modulate it. 5-Amino-1MQ is studied in the literature as an inhibitor of this enzyme.
Describing it as an 'NNMT inhibitor' is a statement about its molecular target in a research context — the enzyme it acts on — not a claim about any downstream effect in a person. It is what makes the compound a useful tool in enzyme and metabolic-pathway studies.
Where it fits on a metabolic bench
Because NNMT touches NAD-related and methylation chemistry, 5-Amino-1MQ is sometimes discussed near NAD-focused research tools. That is a conceptual adjacency in metabolic research, not a functional equivalence — it is a small-molecule enzyme inhibitor, distinct from both the incretin peptides and the NAD compounds it may be mentioned alongside.
These are research areas the compound is associated with in the literature — not medical claims or intended uses.
Handling & storage
Supplied as a small-molecule research chemical. Kept sealed, cool, and dry; prepared per the reagent's own guidance rather than peptide reconstitution practice. Handled per accepted laboratory practice. Research use only.
Verify a certificate by lot →Common questions
No. It is a small-molecule quinolinium compound with no amino-acid sequence. It is grouped in the Metabolic category but is chemically a different class from the peptides there.
It is studied as an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in methylation and NAD-related metabolism. That describes its molecular target in research, not any effect.
Because NNMT sits at a junction of methylation and NAD-related metabolism, so the compound is conceptually adjacent to NAD-focused tools. It remains a distinct small-molecule enzyme inhibitor.
This monograph is a research-use reference. It describes composition and the contexts in which the compound has been studied — it is not medical advice, a description of effects, or a recommendation for use. Sold strictly for laboratory and research use; not for human or animal consumption.